Undated (WBAP/KLIF) – The most prolific serial killer in U.S. history has died. Samuel Little died Wednesday in a California hospital. He was 80 years old, and serving 3 life in prison sentences for multiple murders. Little claimed he killed 93 people between 1970 and 2005, most of them in Florida and California, but several in Texas as well. investigators have confirmed he committed 60 of the killings, and while they are still investigating say they have no reason to doubt he committed the others as well.